en بیوشیمی Biochemistry مقالات اصلی Original Article <div style="text-align: justify;"><strong><em>Background:</em></strong> Polycystic ovary syndrome (PCOS) is a hormonal disorder in women with unknown causes and is the leading cause of infertility in women of reproductive age, presenting a wide range of clinical manifestations worldwide. The objective of study is to compare the correlation between hormones, lipid profile, oxidative stress and Zinc concentration in PCOS patients.<br> <br> <strong><em>Methods:</em></strong> The present study examined hormone levels (progesterone, prolactin, luteinizing and follicle stimulation hormones (LH and FSH, respectively), antioxidant factors (catalase, glutathione-s- transferase), lipid profiles and zinc concentration of 50 Iraqi women patients&rsquo; diagnosis with PCOS and 40 healthy women, divided in two age groups of 15-29 and 30-45 years. Body mass index was estimated for two age groups.<br> <br> <strong><em>Results:</em></strong> The results showed decreasing of catalase, glutathione, and Zn concentrations with an increase in age. A slightly significant increase in LH and prolactin and decrease in high-density lipoprotein (HDL-C) with an increase in age in the patient group compared to the control group was noted.<br> <br> <strong><em>Conclusions:</em></strong> Our study demonstrated that some factors (such as family history, genetics, environmental, etc&hellip;) could play a role in altering hormone levels, lipid profiles, and antioxidant. Controlling these factors may be useful for reducing the PCOS-associated problems in women&rsquo;s health. Needed extensive studies to assess the correlation with insulin resistant and obesity.<strong><span dir="RTL"></span></strong></div> Hormones disorders, Lipid profile, Polycystic ovary syndrome, Zinc element. 270 277 http://rbmb.net/browse.php?a_code=A-10-512-1&slc_lang=en&sid=1 Ashwaq Shenta 100319475328460017655 100319475328460017655 No Department of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq Khansaa Saud 100319475328460017656 100319475328460017656 No Department of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq Ali Al-Shawi ali.abdulhussein@uobasrah.edu.iq 100319475328460017657 100319475328460017657 Yes Department of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq